Fig. 6
From: Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer
Clinical relevance of p-Skp2 (S64) in human gastric cancers. a Representative IHC staining of p-Skp2 (S64) and p-mTOR (S2448) expression in GC; scar bar, 50um. b The correlation between p-mTOR and p-Skp2 expression was analyzed by Spearman rank correlation test (R=0.59; p < 0.01). c Representative GC tissues were extracted and analyzed by western bolt. (d-f) The Kaplan-Meier overall survival curves indicated that p-Skp2 (S64) and p-mTOR (S2448), alone (d, e) and together (f), are associated with a reduction of overall survival in gastric cancer patients