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Table 1 CR-1 expression was positively correlated with clinical pathologic parameter

From: Cripto-1 acts as a functional marker of cancer stem-like cells and predicts prognosis of the patients in esophageal squamous cell carcinoma

Clinicopathological parameter

Case (%)

Expression of CR-1

p Value

CR-1low (%)

CR-1high (%)

Gender

   

0.636

 Male

118(85.5)

24(82.8)

94(86.2)

 

 Female

20(24.5)

5(17.2)

15(13.8)

 

Age (year)

   

0.106

  ≤ 62

66(47.8)

10(34.5)

56(51.4)

 

  > 63

72(52.2)

19(65.5)

53(48.6)

 

Depth of invasion

   

0.002

 Tis + T1

16(11.6)

8(27.6)

8(7.3)

 

 T2 + T3

122(88.4)

21(72.4)

101(92.7)

 

TNM Stage

   

0.001

 0 + I

54(39.1)

19(65.5)

35(32.1)

 

 II + III

84(60.9)

10(34.5)

74(67.9)

 

Lymph node metastasis

   

0.044

 Yes

34(24.6)

3(10.3)

31(28.4)

 

 No

104(75.4)

26(89.7)

78(71.6)

 

Histological grade

   

0.825

 G1

88(63.8)

19(65.5)

69(63.3)

 

 G3 + G2

50(36.2)

10(34.5)

40(36.7)

 
  1. Tis, severe dysplasia; T1, indicates the localization of tumor cells in the esophageal tunica mucosa; T2, indicates the localization of tumor cells in esophageal muscular layer; T3 indicates the invasion of tumor cells in esophageal adventitia; G1, well differentiation; G2, moderate differentiation; G3, poor differentiation
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Molecular Cancer

ISSN: 1476-4598