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Table 1 CR-1 expression was positively correlated with clinical pathologic parameter

From: Cripto-1 acts as a functional marker of cancer stem-like cells and predicts prognosis of the patients in esophageal squamous cell carcinoma

Clinicopathological parameter Case (%) Expression of CR-1 p Value
CR-1low (%) CR-1high (%)
Gender     0.636
 Male 118(85.5) 24(82.8) 94(86.2)  
 Female 20(24.5) 5(17.2) 15(13.8)  
Age (year)     0.106
  ≤ 62 66(47.8) 10(34.5) 56(51.4)  
  > 63 72(52.2) 19(65.5) 53(48.6)  
Depth of invasion     0.002
 Tis + T1 16(11.6) 8(27.6) 8(7.3)  
 T2 + T3 122(88.4) 21(72.4) 101(92.7)  
TNM Stage     0.001
 0 + I 54(39.1) 19(65.5) 35(32.1)  
 II + III 84(60.9) 10(34.5) 74(67.9)  
Lymph node metastasis     0.044
 Yes 34(24.6) 3(10.3) 31(28.4)  
 No 104(75.4) 26(89.7) 78(71.6)  
Histological grade     0.825
 G1 88(63.8) 19(65.5) 69(63.3)  
 G3 + G2 50(36.2) 10(34.5) 40(36.7)  
  1. Tis, severe dysplasia; T1, indicates the localization of tumor cells in the esophageal tunica mucosa; T2, indicates the localization of tumor cells in esophageal muscular layer; T3 indicates the invasion of tumor cells in esophageal adventitia; G1, well differentiation; G2, moderate differentiation; G3, poor differentiation