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Fig. 6 | Molecular Cancer

Fig. 6

From: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer

Fig. 6

HOXA11-AS represses P21 transcription and KLF2 expression by binding with EZH2 and STAU1. a qRT-PCR analysis of STAU1 and KLF2 expression in BGC823 and SGC7901 cells after transfection with STAU1 or NC siRNA. b ChIP-qPCR analysis of EZH2, and H3K27me3 occupancy in the P21 promoter in BGC823 and SGC7901 cells. c ChIP-qPCR analysis of EZH2, and H3K27me3 occupancy in the P21 promoter in BGC823 and SGC7901 cells after transfection with HOXA11-AS or NC siRNA. d qRT-PCR analysis of EZH2 and P21 expression in BGC823 and SGC7901 cells after transfection with EZH2 or NC siRNA. e KLF2 mRNA levels in immunoprecipitates were determined by qRT-PCR. Expression levels of KLF2 mRNA were presented as fold enrichment relative to IgG immunoprecipitates. f KLF2 mRNA levels in immunoprecipitates were determined by qRT-PCR after transfection with HOXA11-AS or NC siRNA. *P < 0.05, **P < 0.01

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Molecular Cancer

ISSN: 1476-4598