Fig. 6
From: HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity
Inhibition of MYC suppresses the phenotypes caused by HN1 overexpression. (a) Mammosphere formation analysis of the self-renewal ability of BCSCs. MCF-7 and T47D cells overexpressing HN1 were exposed to MYC-siRNA and MYC inhibitor 10058-F4 (*P <0.05). b Transwell invasion analysis showed the invasion ability of indicated cells. MCF-7 and T47D cells with overexpression of HN1 were exposed to MYC-siRNA and MYC inhibitor 10058-F4 (*P <0.05). Each bar represents mean ± SD of 3 independent experiments