Skip to main content

Table 2 Univariate and multivariate Cox regression analyses of the 2-lncRNA signature

From: Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma

Characteristics Univariate analysis Multivariate analysis
HRa(95% CI) P-value HR(95% CI) P-value
Training dataset
 2-lncRNA signature 2.59(1.60,4.18) 1.00e–04 2.43(1.49,3.94) 3.45e–04
 Age ≥ 60 vs <60 years 1.41(0.85,2.35) 0.18 1.33(0.79,2.21) 0.28
 Gender female vs male 1.09(0.66,1.81) 0.74 1.10(0.66,1.84) 0.72
 Stage I vs II 2.80(1.27,6.16) 0.011 2.12(0.95,4.74) 0.066
GSE50081
 2-lncRNA signature 1.91(1.11,3.29) 0.020 1.82(1.03,3.22) 0.039
 Age ≥ 60 vs <60 years 1.50(0.64,3.51) 0.35 1.62(0.68,3.87) 0.27
 Gender female vs male 0.74(0.43,1.28) 0.29 0.69(0.39,1.22) 0.20
 Smoking vs never-smoking 1.31(0.73,2.35) 0.36 1.07(0.58,1.97) 0.83
 Stage I vs II 2.54(1.45,4.44) 1.16e–03 2.49(1.40,4.41) 1.83e–03
GSE31210
 2-lncRNA signature 3.29(1.58,6.85) 1.45e–03 2.40(1.12,5.11) 0.024
 Age ≥ 60 vs <60 years 1.47(0.70,3.10) 0.31 1.59(0.76,3.37) 0.22
 Gender female vs male 0.59(0.29,1.22) 0.16 0.97(0.36,2.61) 0.95
 Smoking vs never-smoking 1.91(0.92,3.97) 0.084 1.60(0.59,4.33) 0.35
 Stage I vs II 4.30(2.09,8.83) 7.21e–05 3.42(1.62,7.26) 1.31e–03
  1. aHR, hazard ratio