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Table 2 Structural formulas of PI3K inhibitors
| Classification | Compound | Structural formula | Compound | Structural formula |
|---|---|---|---|---|
| Pan-PI3K inhibitors | Pictilisib (GDC-0941) |
| Copanlisib (BAY 80–6946) |
|
| Taselisib (GDC-0032) |
| Sonolisib (PX-866) |
| |
| Buparlisib (BKM120) |
| ZSTK474 |
| |
| Pilaralisib (XL147, SAR245408) |
| AMG 511 |
| |
| Isoform-selective inhibitors | Alpelisib (BYL719) |
| CH5132799 |
|
| Idelalisib (CAL-101, GS-1101) |
| AS-605240 |
| |
| AMG319 |
| MLN1117 (INK1117) |
| |
| AZD6482 |
| |||
| Dual PI3K/mTOR inhibitors | Dactolisib (NVP-BEZ235) |
| GDC-0084 (RG7666) |
|
| NVP-BGT226 |
| VS-5584 (SB2343) |
| |
| Omipalisib (GSK2126458, GSK458) |
| PF-04691502 |
| |
| GSK1059615 |
| Gedatolisib (PF-05212384, PKI-587) |
| |
| Voxtalisib (XL765, SAR245409) |
| PQR309 |
| |
| Apitolisib (GDC-0980) |
|
