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Table 2 Structural formulas of PI3K inhibitors

From: Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

Classification Compound Structural formula Compound Structural formula
Pan-PI3K inhibitors Pictilisib (GDC-0941) Copanlisib (BAY 80–6946)
Taselisib (GDC-0032) Sonolisib (PX-866)
Buparlisib (BKM120) ZSTK474
Pilaralisib (XL147, SAR245408) AMG 511
Isoform-selective inhibitors Alpelisib (BYL719) CH5132799
Idelalisib (CAL-101, GS-1101) AS-605240
AMG319 MLN1117 (INK1117)
AZD6482   
Dual PI3K/mTOR inhibitors Dactolisib (NVP-BEZ235) GDC-0084 (RG7666)
NVP-BGT226 VS-5584 (SB2343)
Omipalisib (GSK2126458, GSK458) PF-04691502
GSK1059615 Gedatolisib (PF-05212384, PKI-587)
Voxtalisib (XL765, SAR245409) PQR309
Apitolisib (GDC-0980)