Table 3 LncRNAs with a role in cervical cancer
From: Dysregulated expression of long noncoding RNAs in gynecologic cancers
LncRNA | Size (kb) | Locus | Mechanism | Nature | Ref |
|---|---|---|---|---|---|
LncRNA--EBIC | 1.5 | 12q22 | Promotes tumor cell invasion by binding to EZH2 and inhibiting E-cadherin expression | Oncogene | [123] |
GAS5 | 0.651 | 1q25.1 | Hormonal regulation (GR) Tumor | Tumor Suppressor | [127] |
lncRNA-CCHE1 | 2.5 | 10q21.1 | Promotes proliferation by enhancing PCNA | Oncogene | [128] |
lncRNA-LET | 2.6 | 15q24.1 | Predicts overall survival and serves as a potential therapeutic target | Tumor Suppressor |