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Fig. 3 | Molecular Cancer

Fig. 3

From: Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression

Fig. 3

NEAT1 and MALAT1 promoted cell proliferation, migration and invasion in lung cancer cells. a-d Cell proliferation was analyzed by RealTime-Glo viability assay for A549 cells treated with NEAT1 expression vectors (a), MALAT1 expression vectors (b), si-NEAT1 oligo (c) or si-MALAT1 oligo (d) at indicated time points. e-h Cell motility was analyzed by transwell migration and invasion assays for A549 cells treated with NEAT1 expression vectors (e), MALAT1 expression vectors (f), si-NEAT1 oligo (g) or si-MALAT1 oligo (h). Data represent mean ± SEM. P-values were determined by two-tailed Student’s t-test. *P < 0.05; **P < 0.01; ***P < 0.001

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