Table 2 Cox regression analysis of risk factors for cancer-related death in lung cancer patients
Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HRa (95% CIb) | P-valuec | HRa (95% CIb) | P-valuec | |
Oct4/NEAT1/MALAT1 expression | ||||
 Other | 1.00 |  | 1.00 |  |
 +/+/+ | 2.78 (1.21–6.42) | 0.016 | 2.42 (1.05–5.62) | 0.039 |
Age | ||||
  < 65 year-old | 1.00 |  | - e |  |
  ≥ 65 year-old | 1.03 (0.64–1.67) | 0.896 | - e | - e |
Gender | ||||
 Female | 1.00 |  | - e |  |
 Male | 1.50 (0.86–2.61) | 0.150 | - e | - e |
Smoking habit | ||||
 Non-smoker | 1.00 |  | - e |  |
 Smoker | 0.96 (0.54–1.72) | 0.891 | - e | - e |
Tumor typed | ||||
 SCC | 1.00 |  | - e |  |
 ADC | 1.32 (0.74–2.37) | 0.343 | - e | - e |
Stage | ||||
 Stage I-II | 1.00 |  | 1.00 |  |
 Stage III-IV | 1.86 (1.18–2.95) | 0.008 | 1.13 (0.65–1.97) | 0.672 |
T stage | ||||
 T1–2 | 1.00 |  | - e |  |
 T3–4 | 1.42 (0.78–2.59) | 0.249 | - e | - e |
N stage | ||||
 N0 | 1.00 |  | 1.00 |  |
  ≥ N1 | 2.36 (1.48–3.78) | <0.001 | 1.93 (1.10–3.38) | 0.022 |
M stage | ||||
 M0 | 1.00 |  | - e |  |
  ≥ M1 | 1.98 (0.86–4.57) | 0.110 | - e | - e |