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Fig. 4 | Molecular Cancer

Fig. 4

From: STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

Fig. 4

HOXD-AS1 is involved in migration of HCC cells through regulating SOX4. a Expression correlation between HOXD-AS1 (x) and SOX4 (y) in 14 HCC tissues. Data are depicted as probe signal value of global gene expression microarray (R = 0.5807, p = 0.0012). b, c The expression of SOX4 in Huh7 cells with HOXD-AS1 knockdown and SNU449 cells with HOXD-AS1 overexpression. β-actin was used as the loading control. d Migration assays of Huh7 cells with HOXD-AS1 knockdown and SOX4 overexpression. e Migration assays of SNU449 cells with HOXD-AS1 overexpression and SOX4 knockdown. Data in b-e are the means ± SD. *p < 0.05 and **p < 0.01

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