Fig. 3From: Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosisOverexpression of RAB3C increased the number of metastatic nodules in vivo (a-b) A mouse metastasis model was established by intravenous injection of RAB3C-overexpressing cells and vector control cells using (a) CX-1 and (b) SW48 cells. An increased number of metastatic nodules was observed in the lung and kidney in the RAB3C-overexpressing group compared with the control group. Some unusual mitotic figures were also observed in metastatic nodules formed from RAB3C-overexpressing cellsBack to article page