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Fig. 3 | Molecular Cancer

Fig. 3

From: Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis

Fig. 3

Overexpression of RAB3C increased the number of metastatic nodules in vivo (a-b) A mouse metastasis model was established by intravenous injection of RAB3C-overexpressing cells and vector control cells using (a) CX-1 and (b) SW48 cells. An increased number of metastatic nodules was observed in the lung and kidney in the RAB3C-overexpressing group compared with the control group. Some unusual mitotic figures were also observed in metastatic nodules formed from RAB3C-overexpressing cells

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