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Fig. 4 | Molecular Cancer

Fig. 4

From: MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells

Fig. 4

Effects of miR-181a-5p and MEG2 on the proliferation and migration of gastric cancer cells. a Cell proliferation assays were performed after the transfection with anti-miR-control plus control siRNA; anti-miR-181a-5p plus control siRNA; anti-miR-control plus MEG2 siRNA; or anti-miR-181a-5p plus MEG2 siRNA in equal doses. b and c Transwell analysis of MGC803 cells transfected with anti-miR-control plus control siRNA; anti-miR-control plus MEG2 siRNA; anti-miR-181a-5p plus control siRNA; or anti-miR-181a-5p plus MEG2 siRNA in equal doses. b representative image; c quantitative analysis. d Cell proliferation assays were performed after the transfection with pre-miR-control plus control plasmid; pre-miR-control plus MEG2 overexpression plasmid; pre-miR-181a-5p plus control plasmid; or pre-miR-181a-5p plus MEG2 overexpression plasmid in equal doses. e and f Transwell analysis of MGC803 cells transfected with pre-miR-control plus control plasmid; pre-miR-control plus MEG2 overexpression plasmid; pre-miR-181a-5p plus control plasmid; or pre-miR-181a-5p plus MEG2 overexpression plasmid in equal doses. e representative image; f quantitative analysis. *P < 0.05; **P < 0.01; ***P < 0.001

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