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Table 1 LncRNAs and their targets in the regulation of glucose metabolism in cancer

From: Role of long non-coding RNAs in glucose metabolism in cancer

Items

Targets

LncRNAs

Tumor types

References

GLUTs

GLUT1

LncRNA NBR2

Kidney cancer

[32]

 

GLUT4

LncRNA CRNDE

Colorectal neopasia

[33]

Enzymes

HK2

LncRNA PVT1

Osteosarcoma

[34]

 

PKM2

LncRNA H19

Liver cancer

[36]

 

G6P, PEPCK

LncRNA GAS5

Cervical/Hepatocellular cancer

[37]

 

Pyruvate carboxylase

LncRNA GCASPC

Gallbladder cancer

[39]

 

PFKFB2

LINC00092

Ovarian cancer

[40]

Oncogenes

c-Myc

PCGEM1, LncRNA-MIF

various cancer

[42, 43]

HIF

HIF and VHL

LincRNA p21, MALAT1

Hepatocellular/Breast cancer et al

[50, 51]

 

HIF-1α

LncRNA-LET, H19, LINK-A

Breast cancer

[52,53,54]

 

miR-145 and HIF-1α

Linc-ROR

Hepatocellular cancer

[55]

PI3K/AKT

PTEN

PTENpg1, HOTAIR

Prostate/Tongue squamous carcinoma

[65, 66]

 

Akt

ANRIL

Nasopharyngeal carcinoma

[67]

 

Let-7

H19

-

[69]

AMPK

LKB1

LINC00473

Lung cancer

[74]

 

AMPK

LncRNA NBR2

various cancer

[77]

Wnt/Snail

EMT

LncRNA CTD903, UCA1

Colorectal cancer, breast cancer

[80, 81]

STAT

STAT1 and PolyII

NRCP

Ovarian cancer

[82]

 

STAT3

UCA1

Bladder cancer

[86]

p53

Mutant p53, PKM2

LncRNA CUDR

Hepatocarcinogenesis

[94]

 

p53 protein

MEG3, Wrap53

various cancer

[95, 97]

 

p53, hnRNP-K

LincRNA p21, MALAT1

various cancer

[49, 98]

 

p53

Linc-ROR

various cancer

[49]