From: Role of long non-coding RNAs in glucose metabolism in cancer
Items | Targets | LncRNAs | Tumor types | References |
---|---|---|---|---|
GLUTs | GLUT1 | LncRNA NBR2 | Kidney cancer | [32] |
GLUT4 | LncRNA CRNDE | Colorectal neopasia | [33] | |
Enzymes | HK2 | LncRNA PVT1 | Osteosarcoma | [34] |
PKM2 | LncRNA H19 | Liver cancer | [36] | |
G6P, PEPCK | LncRNA GAS5 | Cervical/Hepatocellular cancer | [37] | |
Pyruvate carboxylase | LncRNA GCASPC | Gallbladder cancer | [39] | |
PFKFB2 | LINC00092 | Ovarian cancer | [40] | |
Oncogenes | c-Myc | PCGEM1, LncRNA-MIF | various cancer | |
HIF | HIF and VHL | LincRNA p21, MALAT1 | Hepatocellular/Breast cancer et al | |
HIF-1α | LncRNA-LET, H19, LINK-A | Breast cancer | ||
miR-145 and HIF-1α | Linc-ROR | Hepatocellular cancer | [55] | |
PI3K/AKT | PTEN | PTENpg1, HOTAIR | Prostate/Tongue squamous carcinoma | |
Akt | ANRIL | Nasopharyngeal carcinoma | [67] | |
Let-7 | H19 | - | [69] | |
AMPK | LKB1 | LINC00473 | Lung cancer | [74] |
AMPK | LncRNA NBR2 | various cancer | [77] | |
Wnt/Snail | EMT | LncRNA CTD903, UCA1 | Colorectal cancer, breast cancer | |
STAT | STAT1 and PolyII | NRCP | Ovarian cancer | [82] |
STAT3 | UCA1 | Bladder cancer | [86] | |
p53 | Mutant p53, PKM2 | LncRNA CUDR | Hepatocarcinogenesis | [94] |
p53 protein | MEG3, Wrap53 | various cancer | ||
p53, hnRNP-K | LincRNA p21, MALAT1 | various cancer | ||
p53 | Linc-ROR | various cancer | [49] |