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Fig. 4 | Molecular Cancer

Fig. 4

From: A long non-coding RNA HOTTIP expression is associated with disease progression and predicts outcome in small cell lung cancer patients

Fig. 4

HOTTIP may enhance EZH1 expression by sponging miR-574-5p. a Putative binding site of miR-574-5p in HOTTIP and EZH1 3′-UTR and the site of target mutagenesis we indicated. b miR-574-5p may negatively regulated expression of HOTTIP and EZH1 at mRNA level in H146 cell. c miR-574-5p may negatively regulated expression of EZH1 at protein level in H146 cell. d & g Correlation analysis in SCLC tissues showed that HOTTIP expression is negatively associated with miR-574-5p but positively associated with EZH1 expression. e & f HOTTIP may positively regulated EZH1 expression but negatively regulated miR-574-5p. *, P < 0.05

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Molecular Cancer

ISSN: 1476-4598