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Fig. 3 | Molecular Cancer

Fig. 3

From: Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer

Fig. 3

NORAD can directly bind to miR-125a-3p and inhibit its expression. a NORAD contains a sequence that is complementary to miR-125a-3p; b the expression of NORAD was negatively associated with the expression of miR-125a-3p in 33 PDAC tissues; c miR-125a-3p was upregulated when NORAD was knocked down in SW1990 and PANC-1; d Relative expression of miR-125a-3p was significantly decreased when NORAD was overexpressed in BxPC-3 and Canpan-1, whereas this phenomenon disappeared when the NORAD MRE was mutated. *, statistical significance, P < 0.05, **p < 0.01, ***p < 0.001

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