Fig. 1
From: Generation of stable PDX derived cell lines using conditional reprogramming
CR technology expands PDX derived cell cultures and maintains genetic profile of the parental PDX tumor. a Experimental design for the establishment of PDX cell lines b Representative images of PDX cells growing in co-culture with GFP-expressing 3 T3-J2 cells (arrows). OV0857F (10X), HLXF-036LN (10X), LG0567F (4X), HLXF-056 (10X). c Targeted genetic sequencing revealed that the CR-PDX cell lines maintain key mutations and allele frequency of the parental PDX