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Fig. 5 | Molecular Cancer

Fig. 5

From: RETRACTED ARTICLE: Upregulation of the long non-coding RNA AFAP1-AS1 affects the proliferation, invasion and survival of tongue squamous cell carcinoma via the Wnt/β-catenin signaling pathway

Fig. 5

Inhibition of AFAP1-AS1 decreased the activity of the Wnt/β-catenin pathway and suppressed the expression of EMT-related genes. a The effect of AFAP1-AS1 on the Wnt/β-catenin signaling pathway was analyzed by western blotting with the indicated antibodies in SCC-9 cells transfected with siR-AFAP1-AS1 or control siRNA. b The effect of AFAP1-AS1 on the Wnt/β-catenin signaling pathway was analyzed by western blotting with the indicated antibodies in CAL-27 cells transfected with shR-AFAP1-AS1 or shR-NC. c The effect of AFAP1-AS1 on the expression of EMT-related genes was analyzed by qRT-PCR in SCC-9 cells transfected with shR-AFAP1-AS1 or shR-NC. d The effect of AFAP1-AS1 on the expression of EMT-related genes was analyzed by qRT-PCR in CAL-27 cells transfected with shR-AFAP1-AS1 or shR-NC. The data represent the mean ± SDs of 3 replicates. *Indicates a significant difference between the Mock group and shR-AFAP1-AS1 group, #indicates a significant difference between the shR-NC group and the shR-AFAP1-AS1 group. * P < 0.05; ** P < 0.01; *** P < 0.001; # P < 0.05; ## P < 0.01;### P < 0.001

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