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Fig. 4 | Molecular Cancer

Fig. 4

From: Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

Fig. 4

Stable overexpression of XLOC_000647 significantly reduces tumor growth in vivo. a Tumors removed from the mice 6 weeks after injection of MIA-PaCa-2 or BxPC-3 cells stably transfected with XLOC_000647-pBABE or pBABE, respectively. b Tumor weights are shown as the means ± SD when the tumors were harvested. c The expression of XLOC_000647 in paired tumor tissues was analyzed by qRT-PCR. d Representative images (×100 and ×400) of IHC staining of the tumor. Results showed that overexpression of XLOC_000647 decreased the proliferation index of Ki67. ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598