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Fig. 2 | Molecular Cancer

Fig. 2

From: Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer

Fig. 2

The piR-1245 promotes cell growth, colony formation, migration and invasion and inhibits apoptosis in colorectal cancer cells. HCT116 and SW480 cells were transfected with either piR-1245 RNA oligonucleotides, antisense or scrambled controls. The treated cells or control cells were subsequently used for MTT assay (a), colony formation assay (b), Ki-67 staining (c), Migration and invasion assay (d) and apoptosis assay (e). All the experiments were performed biological triplicate. (*P < 0.05, **P < 0.01; independent t-test was used to compare control and treated cells)

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