Targeting Gas6/TAM in cancer cells and tumor microenvironment

Table 1 Research on targeting Gas6/TAM for cancer therapy

	Therapy	Target	Cancer type	Reference
Specific	R428	Axl	Breast cancer, GBM, AML and Ewing sarcoma	[74, 76,77,78]
	UNC1062	Mer	melanoma	[39]
	UNC2025	Mer	GBM	[87]
	Mer590	Mer	NSCLC	[88]
Non-specific	shRNA	Axl	Breast carcinoma	[65]
	shRNA	Mer	Melanoma and AML	[39, 42]
	siRNA	Tyro3	Breast cancer	[23]

Gas6 growth arrest-specific gene 6, AML acute myeloid leukaemia, GBM glioblastoma multiforme, NSCLC non-small-cell lung cancer

ISSN: 1476-4598