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Table 1 Comparison of the EGFR mutation status between tumor tissue and BALF in EGFR-TKIs naïve patients

From: Extracellular vesicle-derived DNA for performing EGFR genotyping of NSCLC patients

EGFR genotype Tissue BALF (n = 23)
EV DNA cfDNA
Mutant type Wild type Mutant type Wild type
Mutant type 14 (60.9%) 14 (60.9%) 0 10 (43.5%) 0
Wild type 9 (39.1%) 0 9 (39.1%) 4 (17.4%) 9 (39.1%)
Sensitivity(%)(95% CI) 100.0% (85.7–100) 71.4% (51.0–85.7)
Specificity (%) (95% CI) 100.0% (85.7–100) 100.0% (85.7–100)
  1. Abbreviations: CI Confidence interva