Table 1 Comparison of the EGFR mutation status between tumor tissue and BALF in EGFR-TKIs naïve patients
From: Extracellular vesicle-derived DNA for performing EGFR genotyping of NSCLC patients
EGFR genotype | Tissue | BALF (n = 23) | |||
|---|---|---|---|---|---|
EV DNA | cfDNA | ||||
Mutant type | Wild type | Mutant type | Wild type | ||
Mutant type | 14 (60.9%) | 14 (60.9%) | 0 | 10 (43.5%) | 0 |
Wild type | 9 (39.1%) | 0 | 9 (39.1%) | 4 (17.4%) | 9 (39.1%) |
Sensitivity(%)(95% CI) | 100.0% (85.7–100) | 71.4% (51.0–85.7) | |||
Specificity (%) (95% CI) | 100.0% (85.7–100) | 100.0% (85.7–100) | |||