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Table 2 Univariate and multivariate Cox regression analysis for mortality in stage III and IV GC patients

From: The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

Variables Univariate analysis Multivariate analysis
HR (95%CI) P HR (95%CI) P
I-III stage
 Age (≥55 vs. < 55) 0.832(0.447-1.548) 0.562 0.808(0.416-1.572) 0.53
 Sex (Male vs. Female) 0.842(0.453-1.566) 0.587 1.166(0.596-2.284) 0.653
 TNM stage (I-III) 2.157(1.359-3.423) 0.001** 2.208(1.368-3.562) 0.001**
 MACC1 expression(high vs. low and negative) 2.144(1.160-3.963) 0.015* 2.004(1.054-3.809) 0.034*
 MACC1-AS1 expression (high vs. low and negative) 2.194(1.218-3.952) 0.009** 1.913(1.041-3.516) 0.037*
IV stage
 Age (≥55 vs. < 55) 1.121(0.493-2.546) 0.786 1.722(0.675-4.395) 0.255
 Sex (Male vs. Female) 0.971(0.423-2.226) 0.944 2.162(0.726-6.445) 0.166
 MACC1 expression((high vs. low and negative) 2.751(1.155-6.554) 0.022* 2.889(1.122-7.443) 0.028*
 MACC1-AS1 expression (high vs. low and negative) 2.572(1.162-5.692) 0.020* 2.509(1.025-6.143) 0.044*
  1. Abbreviations: HR hazard ratio, CI confidence interval, *P<0.05, **P<0.01