Fig. 7
From: MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling
Overexpression of β-catenin-S33Y mutant rescues MASTL knockdown cells from apoptosis. β-catenin-S33Y mutant was transiently overexpressed (48 h) in MASTL knockdown cells and overexpression of activated β-catenin was confirmed by immunoblotting and topflash reporter assay in HCT116 (a) and SW620 (b) cells. c Caspase-3/7 activity as measured by luminescence in HCT116MKD and SW620MKD cells as compared to control cells and modulation due to overexpression of activated form of β-catenin in these cells