Fig. 1

Structure of human FOXO3a. Letters within the bar indicate structural domains. The well-known proteins interacting with FOXO3a are shown above the lines at the corresponding domains. Only representatives of FOXO3a-interacting proteins are shown. FKH, forkhead winged helix-turn-helix DNA binding domain; TAD, transactivation domain; NLS, nuclear localization sequence; NES, nuclear export sequence