Fig. 3
From: The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
CYTOR promotes tumor growth and metastasis in mouse xenografts. a Volume of Xenograft tumors from BALB/c-nu/nu male mice subcutaneously injected with CYTOR knockdown (shRNA) RKO cells and control (scramble). b Xenograft tumor weight for CYTOR knockdown (shRNA) RKO cells and control (scramble) in the xenograft model. c Tumor growth curves of CYTOR knockdown (shRNA) RKO cells and control (scramble) and in the xenograft model. d Volume of Xenograft tumors from BALB/c-nu/nu male mice subcutaneously injected with control (EV) or CYTOR-overexpressing (CYTOR) HCT116 cells. e Xenograft tumor weight for CYTOR-overexpressing (CYTOR) HCT116 cells and control (EV) in the xenograft model. f Tumor growth curves of control (EV) and CYTOR-overexpressing (CYTOR) HCT116 cells in the xenograft model. g Representative images of luciferase signals in pulmonary metastatic luciferase foci after tail-vein injection of control (scramble) or CYTOR knockdown (CYTOR shRNA) RKO cells in immunodeficient mice