Fig. 1

CircYAP1 acts as an independent prognostic factor for OS in GC patients. a, CircYAP1 expression was significantly lower in GC tissues than in normal adjacent tissues from 17 patients with GC according to qPCR. b, Cellular localization of circYAP1 in GC tissue cells and adjacent normal tissue cells. The nuclei was stained blue with DAPI, and cytoplasmic circYAP1 was stained green. c, CircYAP1 expression levels were lower in GC tissues than in normal tissues. d, CircYAP1 expression levels were higher in early-stage GC patients than in advanced stage GC patients. e-f, Kaplan-Meier analysis of the association of circYAP1 expression levels with the OS of GC patients and late-stage GC patients (stage III + IV). g-h, Kaplan-Meier analysis of the association of circYAP1 expression with the therapeutic outcomes of GC patients and late-stage GC patients (stage III + IV). *P < 0.05; **P < 0.01