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Fig. 6 | Molecular Cancer

Fig. 6

From: Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 Kip1 axis

Fig. 6

CircYAP1 inhibited tumor growth in vivo. a, Nude mice were subcutaneously injected with circYAP1-overexpressing MKN-45 cells and NC cells. b, Schematic representation of the MKN-45 xenograft tumor size after 30 days of tumor growth in the circYAP1 overexpression and NC groups. c, Statistical comparison of the differences in tumor volumes between the circYAP1 overexpression and NC groups. d, HE analysis of the tumor formation in circYAP1 overexpression and NC groups. e, IHC analysis of Ki-67 expression levels in xenograft tumor tissues from the circYAP1 overexpression and NC groups (× 400). f, Loss of circYAP1 sponges and increases the free miR-367-5p levels, and thereby decreased p27 Kip1 expression, leading to the GC tumorigenesis

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Molecular Cancer

ISSN: 1476-4598