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Table 1 Overview of adhesion molecules found on different leukocyte subtypes and their corresponding ligands

From: The functional role of integrins during intra- and extravasation within the metastatic cascade

Leukocyte Adhesion Molecule

Leukocyte Subtype

Ligand

VLA-4 (α4ß1)

Monocytes [39]

Neutrophils in case of sepsis [38]

VCAM-1

MAdCAM-1

JAM-B

LFA-1 (αLß2) (CD11a/CD18)

Neutrophils [39, 42]

Monocytes [43]

ICAM-1

ICAM-2

JAM-A

α4ß7 (CD49d/ß7)

Lymphocytes (CD4 and CD8 T cells) (mucosal lymphoid nodules) [7, 44]

MAdCAM-1

Gp150,95 (αXß2)

(CD11c/CD18)

Monocytes

Macrophages [45]

Granulocytes [46] (Neutrophils [9])

Langerhans cells

iC3b

(JAM-C [47])

αMß2 (mac-1)

(CD11b/CD18)

Monocytes [43]

Macrophages [45]

Granulocytes [48]

(Neutrophils [42])

Langerhans cells [7]

iC3b

ICAM-1

ICAM-2

JAM-C

αDß2

Macrophages (?) [7]

Neutrophils [9]

ICAM-3

CD47

T cell [49]

VCAM-1

ICAM-1

L1-CAM

Lymphocytes [4, 50, 51]

α5ß1 (VLA-5)

αVß3

Glycosylated proteins

(ß-galactose)

Leukocytes [52]

Galectins

  1. Only major ligands are listed