Table 4 Effects of virus on NKG2D expression
From: Natural killer group 2D receptor and its ligands in cancer immune escape
virus | Mechanism | Function | Reference |
|---|---|---|---|
HCMV | HCMV-miR-UL112 interferes with MICB mRNA | MICB↓ | [70] |
JCV, BKV | JCV/BKV miR-J1/B1-3p interferes with ULBP3 mRNA | ULBP3↓ | [71] |
HBV | HBc and HBx promote the expression of GATA-2 and GATA-3 | MICA/B↓ | [72] |
HCV | NS3/4A protein | NKG2DL↓ | [73] |
AdV | E3/19 K protein | NKG2DL stored | [74] |
VSV | n.d | MEI | [75] |
HIV | n.d | sNKG2DLs↑ | [76] |