Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

Table 1 Correlation of relative circAKT3 expression with the clinicopathological characteristics of 105 patients accepted cisplatin-based chemotherapy with gastric cancer

Characteristics	Number	No. of patients		P value
Characteristics	Number	circAKT3^high	circAKT3^low	P value
Age(y)
< 60	62	34	28	0.283
≥ 60	43	19	24
Gender
Male	80	37	43	0.121
Female	25	16	9
Tumor size(cm)
< 3.5	56	21	35	0.004**
≥ 3.5	49	32	17
Histological grade
Well-moderately	33	11	22	0.017*
Poorly-signet	72	42	30
Clinical stage
II	39	13	26	0.007**
III	66	40	26
T classification
T1-T2	31	9	22	0.004**
T3-T4	74	44	30
N classification
N0	14	5	9	0.232
N1-N3	91	48	43
Cisplatin chemosensitivity
Sensitive	92	41	51	0.001**
Resistant	13	12	1