Fig. 4
From: Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Exosome application in cancer therapy. Exosomes derived from DCs could be used to deliver Anti-cancer drugs such as chemotherapeutic agents and functional RNAs including siRNA and microRNA. Moreover, peptides also could be delivered to the target cancer cells especially CSCs. Such examples are TRAIL and mutated survivin. The specific markers of CSCs such as CD44, CD24, CD133, and CD200 can be used as targets for exosomes contain the antibodies against these proteins