Fig. 2From: Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironmentTAM receptor signaling skews macrophage polarization. TAM receptor binding and downstream signaling dampens M1 polarization and promotes M2 polarization. Overall, this decreases anti-tumor M1-like phenotypes and functions and increases pro-tumor M2-like phenotypes and functionsBack to article page