Table 1 Correlation between circTRIM33–12 and clinicopathological characteristics in 200 HCCs
Variable | circTRIM33–12 | P value | |
|---|---|---|---|
Low | High | ||
Age (years) | |||
≤ 50 | 44 | 46 | 1.000 |
> 50 | 56 | 55 | |
Sex | |||
Female | 13 | 17 | 0.553 |
Male | 87 | 83 | |
HBsAg | |||
Negative | 21 | 20 | 1.000 |
Positive | 79 | 80 | |
HCVAb | |||
Negative | 3 | 4 | 1.000 |
Positive | 97 | 96 | |
Liver cirrhosis | |||
No | 87 | 83 | 0.553 |
Yes | 13 | 17 | |
Serum AFP, ng/mL | |||
≤ 20 | 30 | 47 | 0.02 |
> 20 | 70 | 53 | |
Serum ALT, U/L | |||
≤ 75 | 86 | 86 | 1.000 |
> 75 | 14 | 14 | |
Tumor size (diameter, cm) | |||
≤ 5 | 49 | 66 | 0.022 |
> 5 | 51 | 34 | |
Encapsulation invasion | |||
Absent | 38 | 58 | 0.007 |
Present | 62 | 42 | |
Vascular invasion | |||
No | 51 | 73 | 0.002 |
Yes | 49 | 27 | |
Tumor number | |||
Single | 75 | 88 | 0.028 |
Multiple | 25 | 12 | |
TNM | |||
I/ II | 73 | 71 | 0.875 |
III/IV | 27 | 29 | |