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Table 3 Univariate and Multivariate Analyses of Factors Associated with Cumulative Recurrence

From: Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

 

Cumulative Recurrence

 

Multivariate

Factors

Univariate, P

HR

95% CI

P value

Sex (female vs. male)

0.161

  

NA

Age (years) (≤50 vs. > 50)

0.184

  

NA

HBsAg (positive vs. negative)

0.419

  

NA

HCVAb (positive vs. negative)

0.708

  

NA

Liver cirrhosis (yes vs. no)

0.489

  

NA

Serum AFP, ng/mL (≤20 vs. > 20)

0.182

  

NA

Serum ALT, U/L (≤75 vs. > 75)

0.622

  

NA

Tumor size (diameter, cm) (> 5 vs ≤ 5)

< 0.001

2.055

1.335–3.163

0.001

Tumor number (multiple vs. single)

0.131

  

NA

TNM (III/IV vs I/II.)

0.099

  

NA

CircTRIM33–12 expression (high vs. low)

0.001

0.534

0.344–0.830

0.005

  1. NA not adopted, AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen, 95%CI 95% confidence interval, BCLC Barcelona-Clinic Liver Cancer, HR hazard ratio, Cox proportional hazards regression model