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Table 3 Univariate and Multivariate Analyses of Factors Associated with Cumulative Recurrence

From: Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

  Cumulative Recurrence
  Multivariate
Factors Univariate, P HR 95% CI P value
Sex (female vs. male) 0.161    NA
Age (years) (≤50 vs. > 50) 0.184    NA
HBsAg (positive vs. negative) 0.419    NA
HCVAb (positive vs. negative) 0.708    NA
Liver cirrhosis (yes vs. no) 0.489    NA
Serum AFP, ng/mL (≤20 vs. > 20) 0.182    NA
Serum ALT, U/L (≤75 vs. > 75) 0.622    NA
Tumor size (diameter, cm) (> 5 vs ≤ 5) < 0.001 2.055 1.335–3.163 0.001
Tumor number (multiple vs. single) 0.131    NA
TNM (III/IV vs I/II.) 0.099    NA
CircTRIM33–12 expression (high vs. low) 0.001 0.534 0.344–0.830 0.005
  1. NA not adopted, AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen, 95%CI 95% confidence interval, BCLC Barcelona-Clinic Liver Cancer, HR hazard ratio, Cox proportional hazards regression model