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Fig. 6 | Molecular Cancer

Fig. 6

From: Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN

Fig. 6

circSLC8A1 suppresses the growth of bladder cancer tumor in vivo. a Hypodermic injection of T24 cells stably transfected with circSLC8A1 or control vector into nude mice established subcutaneous xenograft tumors (n = 6 for each group). b Representation picture of tumor formation of the xenograft in nude mice. c and d Compared with the vector group, the tumor growth rate and weight significantly decreased in circSLC8A1-treated nude mice. e circSLC8A1, miR-130b, and miR-494 levels were detected by qRT-PCR in tumor tissues. f The expressions of PTEN, AKT, p-AKT, and MMP9 were measured using IHC staining in the xenografts

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Molecular Cancer

ISSN: 1476-4598