Fig. 2
From: Exosomal circRNAs: biogenesis, effect and application in human diseases
Schematic illustration of the role of exosomal circRNAs in cell proliferation. Chronic exposure to arsenite increases exosomal circRNA_100284 levels, which accelerate the cell cycle and promote proliferation by acting on miR217. E2H2 and cyclin D1, promising biomarkers of proliferation, are extensively activated to regulate the G1 to S phase transition, thus inducing cell proliferation