Fig. 2
From: The significance of exosomes in the development and treatment of hepatocellular carcinoma
The detailed mechanism of the role exosomes played in the process of CHB to HCC. a After infection with HBV, the viruses using exosomes secrete some substances that lead to chronic infection with HBV. b During the chronic infection with HBV, the viruses stimulate all kinds of cells to release exosomes, leading to liver cirrhosis (LC). c The concrete mechanism of exosomes during the formation of HCC