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Table 3 MiRNAs and 5-FU resistance in HCC

From: The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

MiRNAs

Expression1

Pathway

Reference

miR-200a-3p

up-regulated

DUSP6

[96]

miR-183

up-regulated

IDH2/SOCS6-HIF-1α

[97]

miR-141

up-regulated

Keap1

[98]

miR-193a-3p

up-regulated

SRSF2

[99]

miR-195

down-regulated

Bcl-w

[100]

miR-125b

down-regulated

Hexokinase II

[101]

Let-7 g

down-regulated

HMGA2

[102]

miR-133a, miR-326

down-regulated

Bcl-xl

[103]

miR-503

down-regulated

EIF4E

[104]

  1. 1miRNAs either up-regulated or down-regulated in resistant hepatocellular carcinoma cells
  2. Note: This table shows 10 miRNAs, their expression level and potential targets in 5-FU resistance of hepatocellular carcinoma
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Molecular Cancer

ISSN: 1476-4598