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Fig. 1 | Molecular Cancer

Fig. 1

From: Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly

Fig. 1

SPOP interacts with Caprin1. a-d Western blot of indicated proteins in WCLs and co-IP samples of anti-FLAG antibody obtained from 293 T cells transfected with indicated plasmids. e Western blot of indicated proteins in WCLs and co-IP samples of IgG or anti-Caprin1 antibody obtained from the cell extracts of C4–2 cells treated with 20 μM of MG132 for 8 h. f Western blot of indicated proteins in WCL and co-IP samples of IgG or anti-SPOP antibody obtained from the cell extracts of C4–2 cells treated with 20 μM of MG132 for 8 h. g Schematic representation of SPOP deletion mutants. Binding capacity of SPOP to Caprin1 is indicated with the symbol. h Western blot of indicated proteins in WCLs and co-IP samples of anti-FLAG antibody obtained from 293 T cells transfected with indicated plasmids

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