Fig. 6

GATA3 mediates the cell proliferation and invasion driven by KIAA1429 or GATA3-AS. a and b CCK-8 assays for indicated cells. c EdU immunofluorescence staining assays for indicated cells. d Cell apoptosis was measured by FITC-Annexin V and PI staining in indicated cells, followed by flow cytometric analysis. e Transwell invasion assays for indicated cells. f Wound-healing migration assays for indicated cells. g and j Tumor volume and tumor weight in subcutaneous xenografts models with indicated cells. Scale bars = 5 mm. k Representative bioluminescence photographs of the murine tail vein injection lung metastasis models at indicated times by imaging with the IVIS@ Lumina II system. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001