Fig. 7

GATA3 mediates the metastasis driven by KIAA1429 or GATA3-AS. a Representative brightfield and fluorescence photographs of pulmonary metastatic nodules in lung metastasis models with indicated cells. Scale bars = 2 mm. b Representative microscopic views of pulmonary metastatic foci from indicated cells in tissue sections of lungs using HE staining. Scale bars = 100 μm. c Representative brightfield and fluorescence photographs of intrahepatic metastatic nodules in orthotopic implantation models with indicated cells. Scale bars = 5 mm. d Representative microscopic views of intrahepatic metastatic foci from indicated cells in tissue sections of livers using HE staining. Scale bars = 100 μm. e and f Schematic Model of the epi-transcriptomic regulation underlying the KIAA1429-GATA3 pathway. Data are presented as mean ± SEM