Skip to main content

Table 2 Univariate and multivariate analysis of Overall Survival (OS) in PDAC patients (n = 166)

From: lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer

Variables Univariate analysis Multivariate analysis
HR 95%CI p-Value HR 95%CI p-Value
Age 0.702 0.485–1.017 0.062    
Gender 0.825 0.582–1.171 0.283    
Differentiation (moderately or poor vs. well) 1.245 0.772–2.008 0.369    
T stage (T3 or T4 vs. T1 or T2) 1.396 0.981–1.986 0.064    
TNM stage (AJCC) (stage II or stage III vs. stage I) 3.250 2.003–5.274 0.001** 1.888 1.001–3.559 0.050
Lymphatic metastasis 2.842 1.928–4.189 0.001** 1.900 1.149–3.140 0.012*
PLACT1 expression 1.645 1.154–2.345 0.006** 1.460 1.017–2.096 0.040*
  1. Abbreviations: HR hazard ratio, 95%CI 95% confidence interval, T stage tumor stage, TNM tumor node metastasis. Cox regression analysis, * p < 0.05, ** p < 0.01