lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer

Table 2 Univariate and multivariate analysis of Overall Survival (OS) in PDAC patients (n = 166)

Variables	Univariate analysis			Multivariate analysis
Variables	HR	95%CI	p-Value	HR	95%CI	p-Value
Age	0.702	0.485–1.017	0.062
Gender	0.825	0.582–1.171	0.283
Differentiation (moderately or poor vs. well)	1.245	0.772–2.008	0.369
T stage (T3 or T4 vs. T1 or T2)	1.396	0.981–1.986	0.064
TNM stage (AJCC) (stage II or stage III vs. stage I)	3.250	2.003–5.274	0.001^**	1.888	1.001–3.559	0.050
Lymphatic metastasis	2.842	1.928–4.189	0.001^**	1.900	1.149–3.140	0.012^*
PLACT1 expression	1.645	1.154–2.345	0.006^**	1.460	1.017–2.096	0.040^*

Abbreviations: HR hazard ratio, 95%CI 95% confidence interval, T stage tumor stage, TNM tumor node metastasis. Cox regression analysis, ^* p < 0.05, ^** p < 0.01

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