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Table 1 Correlation between ALKBH5 expression and clinicopathological features of pancreatic cancer (PC)

From: RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner

Characteristic

No. of patients (%)

ALKBH5 expression

*P

Low n = 22 (%)

High n = 20(%)

Age

 <60

20 (47.6)

12 (54.5)

8 (40.0)

0.346

 ≥60

22 (52.4)

10 (45.5)

12 (60.0)

 

Gender

 Male

19 (45.2)

10 (45.5)

9 (45.0)

0.976

 Female

23 (54.8)

12 (54.5)

11 (55.0)

 

Tumor location

 Head

29 (69.0)

15 (68.2)

14 (70.0)

0.899

 Body/tail

13 (31.0)

7 (31.8)

6 (30.0)

 

Tumor size

 ≥3cm

14 (33.3)

9 (40.9)

5 (25.0)

0.275

 <3cm

28 (66.7)

13 (59.1)

15 (75.0)

 

Differentiation

 Well to moderate

28 (66.7)

11 (50.0)

17 (85.0)

0.016*

 Poor

14 (33.3)

11 (50.0)

3 (15.0)

 

aTNM stage

 I

11 (26.2)

3 (13.6)

8 (40.0)

0.033*

 II

17 (40.5)

8 (36.4)

9 (45.0)

 

 III

14 (33.3)

11 (50.0)

3 (15.0)

 

Vascular invasion

 Absent

24 (57.1)

9 (40.9)

15 (75.0)

0.026*

 Present

18 (42.9)

13 (59.1)

5 (25.0)

 
  1. aThere is no patients with TNM IV stage tumors
  2. *P<0.05 indicates a significant relationship among the variables