Fig. 8
From: CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a
CircMUC16 mediated metastasis of EOC cells in vivo. a Silencing circMUC16 suppressed pelvic peritoneal invasion. The arrow showed the tumor in the abdominal cavity. b Mean tumor weight was calculated. c Immunohistochemical analysis of Beclin1, RUNX1 and ATG13 proteins. d A graphic abstract depicting the circMUC16 pathway (CircMUC16, RUNX1, Beclin1, ATG13 and miR-199a). All experiments were repeated three times. Error bars represent the standard error. The symbols * and ** indicate p < 0.05 and 0.01, respectively. Scale bar: 100 μm