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Table 2 Univariate and multivariate Cox-regression analysis of prognostic factors for CC patients (n = 87)

From: A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer

 

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

T stage

 T1 + T2

1

  

1

  

 T3 + T4

2.28

(1.06,4.91)

0.036*

2.03

(0.93,4.44)

0.074

N stage

 N0

1

  

1

  

 N1 + N2

2.99

(1.63,5.53)

< 0.001***

2.29

(1.21,4.33)

0.011*

Gender

 Male

1

     

 Female

0.76

(0.36,1.58)

0.462

–

–

–

Differentiation

 Well

1

     

 Moderate

1.30

(0.66,2.56)

0.455

–

–

–

 Poor

0.95

(0.38,2.40)

0.914

–

–

–

Expression of circFNDC3B

 High

1

  

1

  

 Low

2.67

(1.43,4.99)

0.002**

2.27

(1.19,4.32)

0.013*

  1. *P < 0.05
  2. **P < 0.01
  3. ***P < 0.001
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Molecular Cancer

ISSN: 1476-4598