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Table 7 miRNAs and resistance to other drugs in gastric cancer

From: Noncoding RNAs in gastric cancer: implications for drug resistance

MiRNAs

Expression1

Genes and Pathways

Drugs

Reference

miR-15b, miR-16

↓

Bcl-2

etoposide, mitomycin

[70]

miR-181b

↓

Bcl-2

etoposide

[71]

miR-497

↓

Bcl-2

etoposide

[72]

miR-200bc/429 cluster

↓

Bcl-2, XIAP

etoposide

[73]

miR-17-92 cluster

↑

 

oxaliplatin/capecitabine

[160]

  1. 1 miRNAs either up-regulated (↑) or down-regulated (↓) in other chemo-drugs resistant gastric cancer cells
  2. Note: This table shows 6 miRNAs whose expression levels and potential targets in other chemo-drugs resistance of gastric cancer.