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Fig. 1 | Molecular Cancer

Fig. 1

From: The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy

Fig. 1

Definition of hyperprogressive disease (HPD): TTF ≤ 2 months, TRG ≥ 2 and/or TGK ≥ 2 (TTF: time to treatment failure; TGR: tumor growth rate; TGK: tumor growth kinetics). The potential biomarkers for HPD after immune checkpoint blockade, including tumor microenvironment biomarkers, clinical indicators and tumor cell biomarkers

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