Fig. 5From: The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapyIn the HPD tumor microenvironment, immunosuppression activity might be stimulated by interaction with M2 TAMs upon PD-1/PD-L1 blockade treatment through activation of Treg cells, promoting apoptosis of effector T cells and increasing recruitment of M2 TAMsBack to article page