Fig. 1
From: RETRACTED ARTICLE: LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis
LncRNA BCRT1 upregulation is associated with advanced progression and poor prognosis in breast cancer. a Heat maps showing the top differentially expressed lncRNAs in breast cancer samples compared to normal tissues (left, GSE112848; right, TCGA). The red shades represent high expression, and green shades represent low expression. b Volcano plots showing the expression profiles of lncRNAs. c-d RT-PCR analysis was used to detect the expression of lncRNA BCRT1 in cell lines and tissues. Actin was the internal control. e Kaplan–Meier analysis showed the association between lncRNA BCRT1 expression and disease-free survival or overall survival of breast cancer patients (n = 68). f The expression level of lncRNA BCRT1 in the subcellular fractions of MDA-MB-231 cells was detected by qRT-PCR. U6 and GAPDH were used as nuclear and cytoplasmic markers, respectively. g The location of lncRNA BCRT1 (red) in MDA-MB-231 cells was determined by FISH assay. DAPI-stained nuclei are blue. (**P < 0.01 and ***P < 0.001)