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Fig. 2 | Molecular Cancer

Fig. 2

From: LINC00173.v1 promotes angiogenesis and progression of lung squamous cell carcinoma by sponging miR-511-5p to regulate VEGFA expression

Fig. 2

Overexpression of LINC00173.v1 predicts early relapse and metastasis in SQC. a Representative sections of LINC00173.v1 in 43 benign lung tissues (eg. granuloma), 248 SQC tissues, 122 ADC tissues and 26 other subtypes of lung cancer including LCNE, ASC, and UDC, using in situ hybridization. Scale bars of 100× magnification, 200 μm and 400× magnification, 50 μm. b The number of 43 benign lung tissues, 248 SQC tissues and 122 ADC tissues stratified by staining index of LINC00173.v1. P value was determined by Fisher’s test or χ2 test. c Staining index of LINC00173.v1 in 43 benign lung granuloma, 248 SQC tissues, 122 ADC tissues and 26 other subtypes of lung cancer tissues. Each bar represents the median values ± quartile values. P value was determined by one-way ANOVA test. n.s. indicates no significance. d to g Kaplan–Meier analysis of progression-free survivals (PFS) (d), overall survival (OS) (e), local relapse-free survival (LRFS) (f) and distant metastasis-free survival (DMFS) (g) in SQC patients with low LINC00173.v1 expression versus high LINC00173.v1 expression. P value was determined by Log-rank test. HR indicates hazard ratio; 95%CI indicates 95% confidence interval

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